产品货号:
Z29721
中文名称:
XIAP抗体
英文名称:
Anti-XIAP Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-XIAP Antibody |
指标别名 | API3;BIRC4;hIAP 3;hIAP3;hILP;IAP 3;IAP like protein;IAP3;ILP;ILP1;MIHA;X linked IAP;XIAP;XLP2 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | XIAP |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human XIAP recombinant protein (Position:A15-V244).Human XIAP shares 89.4% and 90.7% amino acid (aa) sequence identity with mouse and rat XIAP,respectively. |
实际分子量 | 55KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | XIAP,also known as IAP3 or BIRC4,is a protein that stops apoptotic cell death.It is mapped to chromosome Xq25.This gene encodes a protein that belongs to a family of apoptotic suppressor proteins.Members of this family share a conserved motif termed,baculovirus IAP repeat,which is necessary for their anti-apoptotic function.This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione,a potent inducer of free radicals,and interleukin 1-beta converting enzyme.This protein also inhibits at least two members of the caspase family of cell-death proteases,caspase-3 and caspase-7.Mutations in this gene are the cause of X-linked lymphoproliferative syndrome.Alternate splicing results in multiple transcript variants. |
Uniprot ID | P98170 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | X-linked inhibitor of apoptosis |
蛋白名全称 | E3 ubiquitin-protein ligase XIAP |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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